The novel once-daily kappa opioid receptor antagonist navacaprant significantly reduced symptoms of depression and anhedonia in participants with moderate-to-severe major depressive disorder in a phase II study, developer Neumora Therapeutics announced.
Could prescribing psychostimulants help patients struggling with illegal stimulant use? (CMAJ)
Working for over 50 years, a 96-year-old psychiatrist is still practicing medicine out of her Illinois home. (Chicago Tribune)
Over in the U.K., there’s been a 20-fold increase in ADHD diagnoses among men ages 18 to 29 from 2000 to 2018, with a nearly 50-fold increase in prescriptions. (BJPsych Open)
Augmented depression therapy — a type of solution-focused targeted talk therapy — edged out traditional cognitive behavioral therapy for improving symptoms of anhedonic depression and was cost-effective in a pilot trial. (eClinicalMedicine)
According to a meta-analysis of 15 studies, functional family therapy didn’t seem to provide much benefit — but also didn’t hurt youths with behavioral problems or their families. (Campbell Systematic Reviews)
A new Ohio law requires school sports coaches to complete training in mental health support for students. (Fox News)
Seasonal patterns emerged for teen suicidality — including self-harm, suicidal ideation, and suicide attempts — hitting peaks in April and October, but hit their lowest when schools shut down during the COVID-19 pandemic. (JAMA Network Open)
Indiana police are asking the state to revoke the license of a new addiction treatment center after three patients died within a week. (AP)